Pilgrim59
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Depends on how you wanna work it. Genetic mutations, their environments, personality, emotional experience, etc. - all play a part in shaping their abilities. As to what and how, you have the liberty to decide.What decides what abilities they receive? Is it basically like a poisoning and they try to make the best out of it?
Promethean's abilities are a poison in a sense. The stronger the ability, the more they'd have to "cook" themselves. Use the cancer to fight the cancers. Which is also the reason why most Prometheans are on certain blockers (drugs) to temporarily slow down the cancer-spread process in combat.